Cardiovascular Pathobiology

Studies related to endothelial cell pathobiology and cardiovascular disease are well represented in AJP, which has topic categories in Cardiovascular, Pulmonary, and Renal Pathology, as well Vascular Biology, Atherosclerosis, and Endothelium Biology. This collection includes original research articles as well as some review articles in the field that have attracted exceptional attention. The full text of these articles is free to all readers. Also free to enjoy are eight review articles by experts in the field that appeared in the November 2021 Small Blood Vessel Disease in the Brain Theme Issue (

Curated Collections From The American Journal of Pathology
Recent Developments in Vascular Adventitial Pathobiology: The Dynamic Adventitia as a Complex Regulator of Vascular Disease
Endothelial Cell Calcium Signaling during Barrier Function and Inflammation
Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice
The Renin-Angiotensin-Aldosterone System (RAAS) Is One of the Effectors by Which Vascular Endothelial Growth Factor (VEGF)/Anti-VEGF Controls the Endothelial Cell Barrier
Mechanisms of Endothelial Regeneration and Vascular Repair and Their Application to Regenerative Medicine
Lack of Endothelial Nitric Oxide Synthase Accelerates Ectopic Calcification in Uremic Mice Fed an Adenine and High Phosphorus Diet
Treatment of Experimental Choroidal Neovascularization via RUNX1 Inhibition
Macrophage–Hypoxia-Inducible Factor-1α Signaling in Carotid Artery Stenosis
Vascular Endothelial Cells Produce Coagulation Factors That Control Their Growth via Joint Protease-Activated Receptor and C5a Receptor 1 (CD88) Signaling
Deletion of LDLRAP1 Induces Atherosclerotic Plaque Formation, Insulin Resistance, and Dysregulated Insulin Response in Adipose Tissue
Small Blood Vessel Disease in the Brain Theme Issue - Nov 2021