Cancer

Original research papers focusing on cancer pathogenesis appear in AJP’s topic category of Tumorigenesis and Neoplastic Progression, as well as in categories devoted to specific organ systems. This compendium marshals a variety of cancer-related papers from the previous two years and underscores the depth and breadth of AJP content in this area. The full text of all listed papers is available gratis.

Curated Collections From The American Journal of Pathology

PIM Kinases Promote Survival and Immune Escape in Primary Mediastinal Large B-Cell Lymphoma through Modulation of JAK-STAT and NF-κB Activity

Thrombopoietin Promotes Angiogenesis and Disease Progression in Patients with Multiple Myeloma

Gene Expression in Solitary Fibrous Tumors (SFTs) Correlates with Anatomic Localization and NAB2-STAT6 Gene Fusion Variants

YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice

Bladder Cancer Invasion Is Mediated by Mammalian Target of Rapamycin Complex 2–Driven Regulation of Nitric Oxide and Invadopodia Formation

Co-Expression and Functional Interactions of Death Receptor 3 and E-Selectin in Clear Cell Renal Cell Carcinoma

Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer

Toll-Like Receptor 3 Overexpression Induces Invasion of Prostate Cancer Cells, whereas Its Activation Triggers Apoptosis

ZNF33A Promotes Tumor Progression and BET Inhibitor Resistance in Triple-Negative Breast Cancer

Resolvin E1 Reduces Tumor Growth in a Xenograft Model of Lung Cancer

Overexpression of Estrogen Receptor α in Mammary Glands of Aging Mice Is Associated with a Proliferative Risk Signature and Generation of Estrogen Receptor α–Positive Mammary

Inhibition of Heat Shock Factor 1 Signaling Decreases Hepatoblastoma Growth via Induction of Apoptosis

DANCR Induces Cisplatin Resistance of Triple-Negative Breast Cancer by KLF5/p27 Signaling