Renal and Urological Pathobiology

This compendium celebrates a decided strength of The American Journal of Pathology, with three Associate Editors devoted to evaluation of manuscripts focusing on diseases of the kidney or genitourinary system. Such articles appear in topic categories that include Cardiovascular, Pulmonary, and Renal Pathology; Metabolic, Endocrine, and Genitourinary Pathobiology; and Tumorigenesis and Neoplastic Progression. This collection comprises original research papers published in the last two years that have been highly cited or received recognition as Editor’s Choice articles, and the full text of all is available free of charge.

Curated Collections From The American Journal of Pathology

Podocytopathy and Nephrotic Syndrome in Mice with Podocyte-Specific Deletion of the Asah1 Gene

Automated Detection and Grading of Non–Muscle-Invasive Urothelial Cell Carcinoma of the Bladder

A Deep Learning-Based Approach for Glomeruli Instance Segmentation from Multistained Renal Biopsy Pathologic Images

Bladder Cancer Invasion Is Mediated by Mammalian Target of Rapamycin Complex 2–Driven Regulation of Nitric Oxide and Invadopodia Formation

Exosome Biogenesis and Lysosome Function Determine Podocyte Exosome Release and Glomerular Inflammatory Response during Hyperhomocysteinemia

Single-Cell Transcriptomics Reveal Disrupted Kidney Filter Cell-Cell Interactions after Early and Selective Podocyte Injury

Co-Expression and Functional Interactions of Death Receptor 3 and E-Selectin in Clear Cell Renal Cell Carcinoma

Single-Nucleus Transcriptional Profiling of Chronic Kidney Disease after Cisplatin Nephrotoxicity

Netrin-1 Overexpression Induces Polycystic Kidney Disease: A Novel Mechanism Contributing to Cystogenesis in Autosomal Dominant Polycystic Kidney Disease

Amelioration of Murine Diabetic Nephropathy with a SGLT2 Inhibitor Is Associated with Suppressing Abnormal Expression of Hypoxia-Inducible Factors

Periprostatic Adipose Tissue Displays a Chronic Hypoxic State that Limits Its Expandability

Barrier-Forming Potential of Epithelial Cells from the Exstrophic Bladder