Neuropathology

Studies of diseases that affect the nervous system have always found a welcoming home in the pages of The American Journal of Pathology. In fact, AJP’s immediate past Editor-in-Chief, Kevin Roth, is a renowned neuropathologist. This compendium brings together a sampling of articles in this field, which appear in topic categories such as Neurobiology and Tumorigenesis and Neoplastic Progression. These selections are freely available to all readers.

Curated Collections From The American Journal of Pathology

Retinal Vascular Abnormalities and Microglia Activation in Mice with Deficiency in Cytochrome P450 46A1–Mediated Cholesterol Removal

Disruption of Purinergic Receptor P2X7 Signaling Increases Susceptibility to Cerebral Toxoplasmosis

Spexin/NPQ Induces FBJ Osteosarcoma Oncogene (Fos) and Produces Antinociceptive Effect against Inflammatory Pain in the Mouse Model

Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in a Triple Transgenic Mouse Model of Alzheimer Disease

Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4

Identification of Lacrimal Gland Postganglionic Innervation and Its Regulation of Tear Secretion

The Single Administration of a Chromophore Alleviates Neural Defects in Diabetic Retinopathy

CD4+ T-Cell Responses Mediate Progressive Neurodegeneration in Experimental Ischemic Retinopathy

Leukemia-Associated Rho Guanine Nucleotide Exchange Factor and Ras Homolog Family Member C Play a Role in Glioblastoma Cell Invasion and Resistance

Decreased Proteasomal Function Induces Neuronal Loss and Memory Impairment

Emergent White Matter Degeneration in the rTg-DI Rat Model of Cerebral Amyloid Angiopathy Exhibits Unique Proteomic Changes

Apolipoprotein E Proteinopathy Is a Major Dementia-Associated Pathologic Biomarker in Individuals with or without the APOE Epsilon 4 Allele