Pathobiology 2027

Mechanisms of Disease

May 1-4, 2027

Flamingo Las Vegas, Las Vegas, NW

Session 029 – Imaging the Dynamic Tumor Ecosystem: From Cells to Circuits

10:30 AM-12:15 PM
Sponsored by the Neoplasia, Tumor Microenvironment, and Metastasis Scientific Interest Group
Session Room: TBD

Session Co-Chairs

Sanjukta Chakroborty

Sanjukta Chakraborty, PhD
Texas A&M Health

Piyali Dasgupta

Piyali Dasgupta, PhD
Marshall University

Session Overview

Recent advances in imaging, from single-cell and subcellular resolution to whole-tissue and systems-level visualization has transformed our ability to decipher the complexity of cancer. This symposium will showcase cutting-edge imaging technologies and integrative analytical approaches that enable investigators to visualize, quantify, and model the dynamic tumor ecosystem across biological scales all the way from “cells to circuits.” Experts in metabolic imaging, multiplexed spatial imaging, intravital microscopy, and computational image analysis will highlight how these complementary approaches reveal cellular signaling, immune interactions, and tissue remodeling that drive tumor progression, metastasis, therapeutic response, and resistance. Together, these advances are reshaping our understanding of cancer biology and accelerating the development of more precise therapeutic strategies.

Agenda

  • Co-Chair – Welcome and Introductions

  • Pavithra Viswanath10:30-10:55 AM
    Tumor-Derived Lactate Drives Immunosuppressive TAM Formation Via a Fructose-SPP1 Axis, Revealing a Therapeutic Vulnerability and Enabling Cell-Type-Specific Imaging in Gliomas
    Pavithra Viswanath, PhD
    University of California, San Francisco

  • Kevin Eliceiri10:55-11:20 AM
    Data-Driven Computational Imaging of the Collagen-Rich Tumor Microenvironment
    Kevin Eliceiri, PhD
    University of Wisconsin

  • Arvind Pathak11:20-11:45 AM
    From Cells to Ecosystems: Imaging the Tumor Microenvironment Across Scales
    Arvind Pathak, PhD
    The Johns Hopkins University School of Medicine

  • 11:45 AM-12:00 PM
    Abstract 1

  • 12:00-12:15 PM
    Abstract 2