Pathobiology 2027

Mechanisms of Disease

May 1-4, 2027

Flamingo Las Vegas, Las Vegas, NW

Session 012 – Pathobiology for Basic Scientists Course: Alternatives to Animal Research – Organoids, Organs-on-a-Chip, and In Silico Research

10:30 AM-12:15 PM
Sponsored by the ASIP Education Committee
Session Room: TBD

Session Co-Chairs

Mahboubeh Varmazyad

Mahboubeh Varmazyad, PhD
University of Pittsburgh School of Medicine

Matthew McMillin

Matthew McMillin, PhD
Baylor College of Medicine

Richard Mitchell

Richard Mitchell, MD, PhD
Brigham and Women’s Hospital, Harvard Medical School

Session Overview

The Pathobiology for Basic Scientists Course this year will cover the topic of Alternatives to Animal Models for Pathology Research. The goal of this session will be to describe emerging technologies such as organ-on-a-chip, organoids, and in-silico modeling as viable alternatives to utilizing animal models for pathology research. The session provides opportunities for interactions between experts in the field, experimental pathology researchers, and trainees.

Agenda

  • Co-Chair – Welcome and Introductions

  • Girija Goyal10:30-10:55 AM
    Organ Chips for Drug Discovery and Clinical Mimicry
    Girija Goyal, PhD
    Harvard University

  • Amy Engevik10:55-11:20 AM
    Mini Organs, Major Insights: Gastrointestinal and Liver Organoids in Pathobiology
    Amy Engevik, PhD
    Medical University of South Carolina

  • Yu-Chiao (Chris) Chiu11:20-11:45 AM
    In Silico Models as Alternatives to Animal Models in Drug Response Research
    Yu-Chiao (Chris) Chiu, PhD
    University of Pittsburgh School of Medicine