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What Is A Physician Scientist
in Pathology and Laboratory Medicine? |
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A physician scientist in Pathology and Laboratory
Medicine is a laboratory physician who is trained in both scientific
investigation and in pathology and/or laboratory medicine, with or without
subspecialty training. The reason to train physician scientists is dual. On
the one hand, the physician scientist brings the rigors of scientific
investigation into the patient care arena and on the other hand, the
physician scientist's contact with disease brings clinically relevant
questions into the research arena to drive investigations into pathogenesis,
prevention, diagnosis, prognosis and treatment of disease. Physician
scientists form a core group who can instill the core values of academic
laboratory medicine into medical students and young trainees. In addition,
physician scientists are able to provide leadership in providing the public
information on how biomedical science is translated into public benefit.
Who better to study disease than those who know it intimately? Who better to
provide clinical care than those who have a facility with problem solving,
hypothesis testing, and critical thinking? Both clinical care and research
benefit enormously from this cross fertilization of knowledge and critical
thinking. In fact, it is not uncommon that normal biological processes
become better understood due to the study of the pathobiology of disease. In
addition, the physician scientist is perfectly suited to the role of a
transmitter of basic and clinical knowledge, especially new and emerging
knowledge. The linking of high quality teaching with innovative high impact
research is a very powerful educational approach to prepare medical students
and residents for self directed learning that will serve them throughout
their career.
Health care is undergoing dramatic changes as biomedical research and
technology allow us to critically explore prevailing concepts and discover
new knowledge to advance new paradigms. In addition, much more consideration
is being given to social, cultural, and outcome parameters of health care
delivery. Pathology and laboratory medicine have led the way in the past
several years to chart the new frontiers of academic medicine - in teaching,
research, and clinical care. In the clinical sphere, advanced laboratory
technologies are being developed and adapted to diagnose disease earlier,
more accurately and with a greater ability to predict outcomes.
These new technologies provide laboratory physicians additional important
information that improve clinical consultations to diagnose disease early
and to direct therapy in ways that surpass anything that has been available
until now. The clinical tissue and human biologic material that pathologists
and laboratory physicians see on a daily basis in their clinical practice
provide intellectual inspiration and direction to investigate mechanisms of
human disease in novel and productive ways. These investigations have led to
quantum leaps in knowledge and understanding of pathogenesis.
By being at the crossroads of basic science and clinical medicine,
pathologists are in the enviable position of understanding how to develop
appropriate in vitro and in vivo models to investigate complex mechanisms of
human disease. The phenotypes arising from genetic manipulation are being
thoroughly studied, including using imaging methods that effectively combine
morphology and molecular biology, a powerful combination to understand
genomic and proteomic function. Thus, laboratory physician scientists are in
an excellent position to generate and effectively communicate new
discoveries and state-of-the-art knowledge to the clinical arena. In fact,
it is only through high-quality research that health care costs will be
controlled by reducing the burden of disease in the population.
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