Launching Your Physician Scientist Career:
Once you arrive in your new position, be prepared for some frustration. By being well informed however, you can successfully navigate through the pitfalls of setting up a new office, research laboratory, and clinical practice. A few months free of clinical duties and teaching is very useful in allowing you to set up your laboratory. Be very familiar with regulations - department, university, government, and funding agencies. Spending time reading guidelines is not what you want to do, however it will save you much grief and will speed up your set up. 
Be familiar with the regulatory guidelines and when in doubt seek information. Ask for advice. Identify administrators and faculty who can be most helpful to you during your start up period. Those faculty who have just set up their laboratory are very useful advisors. We can all learn from someone else's experiences. Good luck!